[Vasoactive intestinal polypeptide (V.I.P)].
نویسنده
چکیده
VIPomas can occur as part of the type 1 multiple endocrine neoplasia (MEN) syndrome. VIP is the principal mediator of the watery diarrhea syndrome (also known as pancreatic cholera, Werner-Morrison syndrome, or diarrheogenic islet cell tumor). Watery diarrhea syndrome, with elevated VIP, has also been associated with neurogenic tumors (ganglioneuroma, neuroblastoma, pheochromocytoma), bronchogenic tumors, and islet cell hyperplasia.
منابع مشابه
Effect of an Antagonist of Vasoactive Intestinal Polypeptide on Biological Rhythm of Rest Activity in the Rat
Abstract Vasoactive Intestinal Polypeptide (VIP), has been found in different neurotransmitter systems and exists in various nerve tracts in the brain. Potential role of this peptide in physiological processes such as regulation of sleep and wakefulness, and biological rhythms has been confirmed in several reports. In the present research effects of intracerebroventricular (ICV) injection of a...
متن کاملEffect of immunisation against vasoactive intestinal polypeptide on gastric corpus tone and motility in the ferret.
The role of vasoactive intestinal polypeptide in the control of gastric corpus tone and motility was investigated using auto-antibodies to neutralise endogenous vasoactive intestinal polypeptide. Six ferrets were immunised with vasoactive intestinal polypeptide thyroglobulin conjugate in Freund's complete adjuvant which resulted in a significant increase in plasma vasoactive intestinal polypept...
متن کاملEffect of intraventricular administration of vasoactive intestinal polypeptide on body temperature in the rat.
Intracerebroventricular injection of vasoactive intestinal polypeptide (VIP) into rat caused a temporary elevation of body temperature followed by a decrease to below the control level. Hypothermia induced by cholecystokinin octapeptide was abolished by simultaneous administration of VIP. Hypothermia following pentobarbital administration was reduced by successive injections of VIP. The results...
متن کاملMixed pancreatic apudoma with symptoms of excess vasoactive intestinal polypeptide and insulin: improvement of diarrhoea with metoclopramide.
A female patient is described with a single pancreatic tumour producing vasoactive intestinal polypeptide (VIP), insulin, and pancreatic polypeptide. The initial presentation was with diarrhoea and hypokalaemia and a raised plasma VIP was demonstrated. Her symptoms improved with metoclopramide administration and absolute concentrations of 28 aminoacid (peak IV) VIP were found to have fallen. Sh...
متن کاملSubstance P and vasoactive intestinal polypeptide in the streptozotocin-induced diabetic rat retina.
PURPOSE Little knowledge exists about how neurotransmitters behave in the diabetic retina. In this study, the authors measured the concentration of two neuropeptides, substance P and vasoactive intestinal polypeptide, in the streptozotocin-induced diabetic rat retina in a time-dependent manner. METHODS The retinas of 1-, 3-, 5-, 8-, and 12-week diabetic rats were processed using a highly sens...
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ورودعنوان ژورنال:
- Acta gastroenterologica Latinoamericana
دوره 8 2 شماره
صفحات -
تاریخ انتشار 1978